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FlyNet: Full integrated network
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Gold Standard: Positive functional gene associations
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Component networks: Individual networks derived directly from
D. melanogaster data
Network | Description | Data sources | Genes | Links |
DM-CC | Co-citation of two genes across Medline and PubMed Central | MEDLINE/PubMed: 2014 baseline, PubMed Cetral: full texts, May 2014 | 6,027 | 503,475 |
DM-CX | Co-expression of two genes in high-dimensional gene expression data | 53 GEO series(GSE) of 1,873 experiments using Affymetrix DNA-chip, obtained in Jan 2014 | 11,718 | 275,033 |
DM-DC | Co-occurrence of protein domains between two genes | Interpro release v46.0 | 4,407 | 7,604 |
DM-GN | Proximity between orthologs of two genes above Prokaryotic genomes (i.e. Gene Neighborhood) | Genome maps of completely sequenced Prokaryotes, obtained from NCBI in 2012 | 1,979 | 15,820 |
DM-HT | Protein-protein interaction(PPI); High-throughput experiments | iRefWeb v13.0 | 7,759 | 25,519 |
DM-LC | Protein-protein interaction(PPI); Literature-curated small-scale expreiements | iRefWeb v13.0 | 1,202 | 2,226 |
DM-PG | Co-inheritance pattern of orthologs of two genes (i.e. Phylogenetic profiling) | protein coding genomes of completely sequenced organisms, obtained in 2012 | 3,357 | 80,506 |
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Component networks: Individual networks derived from networks of other organisms' (
Associalogs)
Network | Description (Association between D. melanogaster orthologs) | Data sources | Genes | Links |
AT-CC | Co-citation links in A. thaliana network (AraNet) | AraNet v2 | 1,747 | 17,501 |
AT-CX | Co-expression links in A. thaliana network (AraNet) | AraNet v2 | 1,105 | 9,455 |
AT-HT | High-throughput PPI in A. thaliana network (AraNet) | AraNet v2 | 1,013 | 2,823 |
AT-LC | Literature curated PPI in A. thaliana network (AraNet) | AraNet v2 | 856 | 1,977 |
CE-CX | Co-expression links in C. elegans network (WormNet) | WormNet v3 | 1,434 | 17,497 |
DR-CX | Co-expression links in D. rerio network (DanioNet) | DanioNet v1 (Unpublished) | 3,223 | 55,515 |
HS-CX | Co-expression links in H. sapiens network (HumanNet) | HumanNet v2 (Unpublished) | 3,366 | 32,482 |
HS-HT | High-throughput PPI in H. sapiens network (HumanNet) | HumanNet v2 (Unpublished) | 2,741 | 12,520 |
HS-LC | Literature curated PPI in H. sapiens network (HumanNet) | HumanNet v2 (Unpublished) | 5,254 | 50,488 |
SC-CC | Co-citation links in S. cerevisiae network (YeastNet) | YeastNet v3 | 2,449 | 48,473 |
SC-CX | Co-expression links in S. cerevisiae network (YeastNet) | YeastNet v3 | 1,674 | 18,488 |
SC-GT | Genetic interactions in S. cerevisiae network (YeastNet) | YeastNet v3 | 1,254 | 6,482 |
SC-HT | High-throughput PPI in S. cerevisiae network (YeastNet) | YeastNet v3 | 1,622 | 18,300 |
SC-LC | Literature curated PPI in S. cerevisiae network (YeastNet) | YeastNet v3 | 2,016 | 16,481 |
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Spatiotemporal specific networks (Developmental Stage-specific and Tissue-specific)
Networks | Description | # Genes | # Links |
ST-EB | Embryo Developmental Stage-specific Network | 3,183 | 7,169 |
ST-LV | Larvae Developmental Stage-specific Network | 1,316 | 2,135 |
ST-PP | Pupae Developmental Stage-specific Network | 1,250 | 1,892 |
ST-AD | Adult Developmental Stage-specific Network | 4,766 | 14,445 |
ST-ID | Imaginal Disc Tissue-specific Network | 1,004 | 1,160 |
ST-CN | Central Nervous System Tissue-specific Network | 1,108 | 1,613 |
ST-SG | Salivary Gland Tissue-specific Network | 667 | 805 |
ST-FB | Fat Body Tissue-specific Network | 2,051 | 3,314 |
ST-DS | Digestive System Tissue-specific Network | 1,981 | 3,758 |
ST-CC | Carcass Tissue-specific Network | 1,537 | 2,421 |
ST-HD | Heads Tissue-specific Network | 2,062 | 3,741 |
ST-AC | Accessory Gland Tissue-specific Network | 556 | 632 |
ST-OV | Ovaries Tissue-specific Network | 402 | 455 |
ST-TT | Testes Tissue-specific Network | 1,010 | 1,036 |